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According to West, in China a two-month course of nicotine-replacement gum costs the equivalent of about $230 while 20 cigarettes can cost as little as 15 cents. West states he ended up being interested in studying Tabex after discovering of the drug from Polish epidemiologist Witold Zatonski, MD, of the Cancer Center and Institute of Oncology in Warsaw."He had been going to conferences for a number of years informing anybody who would listen that this drug worked," West says.

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Neither the smokers nor the scientists understood which treatment was being provided. A year later on, 8. 4% of the study participants taking Tabex had successfully quit cigarettes compared to 2. 4% of the individuals taking the placebo. West states a significant strength of the study was that it was openly funded through a grant from the U.K.'s Medical Research Council.

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if authorized by the FDA. He adds that the firm will probably require more studies of the drug prior to taking any action. Tabex was established and is marketed by the Bulgarian pharmaceutical business Sopharma, and it has been accredited to Maryland-based Extab Corp. According to Extab's website, the company's sole function is to acquire approval for the drug in the U.S.

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Cigarette smoking cessation specialist Michael C. Fiore, MD, agrees that more research study is required before the drug is approved in the U.S.Fiore directs the University of Wisconsin Center for Tobacco Research and Intervention in Madison."This is a promising first research study that needs to be duplicated," he tells Web, MD. "A really low-cost generic drug that is both safe and effective would be a very practical addition to smoking cigarettes cessation efforts in the United States."Fiore states cigarette smokers who wish to stop have the best possibility of prospering when they integrate medication with counseling.

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The total objectives of this study are to 1) evaluate awareness of interest in making use of pharmacotherapy for smoking cessation in Croatia and Slovenia, nations in Central Europe with really high smoking prevalence, and 2) examine whether cytisine is at least as possible and efficient as varenicline in helping smokers to stop in a real-life setting: household medication practices in Croatia and Slovenia.